Lifescience Global

jao

product-logo-jao 1340476205

Strength Training as an Adjunct to the Maintenance of Muscle Mass in Patients with Head and Neck CancerPages 22-24
Adilson Domingos dos Reis Filho, Fernando Tadeu Trevisan Frajacomo, Roberto Carlos Vieira Junior, Haracelli Christina Barbosa Alves Leite da Costa, James Wilfred Navalta, Ramires Alsamir Tibana, Jonato Prestes and Fabrício Azevedo Voltarelli

https://doi.org/10.6000/1927-7229.2018.07.02.1

Published: 17 April 2018


Abstract: Head and neck cancer (HNC) is one of the most common types of the disease, particularly among men, and is characterized by a high incidence of death. Among the non-pharmacological factors that help in survival and improving quality of life is physical exercise, especially strength training. The purpose of this short communication was to briefly review the literature and present a training proposal for oncology patients with HNC. Evidence is provided that physical exercise, mainly short-term strength (HIIT [High-Intensity Interval Training]) and aerobic training, contributes to increased expectation and quality of life in cancer survivors. After reviewing the current state of literature, we conclude that strength training, by providing maintenance of muscle mass, improves the autonomy and quality of life of oncology patients with HNC.

Keywords: Cancer, exercise, strength training, health.

Download Full Article

product-logo-jao 1340476205

Myeloid Derived Suppressor Cells in Oral Cancer: An Emerging ConceptPages 25-28

T.G. Shrihari

https://doi.org/10.6000/1927-7229.2018.07.02.2

Published: 17 April 2018


Abstract: Myeloid derived suppressor cells (MDSC) are specialized immunoregulatorycells and major cause of immunosuppression in oral cancer tumor microenvironment. Which are generated by various mediators of chronic inflammation. MDSC exerts its effects by two mechanisms, first is enzymatic mechanism by two enzymes which are elevated in MDSC are arginaseand iNOS2, second is non-enzymatic mechanism by ROS, peroxynitrate ,L-selectin and interaction with other immune cells. It also has a role in progression of oral cancer by secreting inflammatory mediators. This article brief about the MDSC in immune regulation and tumor progression in oral cancer tumor microenvironment.

Keywords: iNOS, Arginase 1, COX-2, HIF-1 Alfa, T regs, Peroxynitrate, S 100 A8/A9, ROS.

Download Full Article

product-logo-jao 1340476205

Inflammation and Cancer: Critical ViewPages 32-36

T.G. Shrihari

https://doi.org/10.6000/1927-7229.2018.07.02.4

Published: 17 April 2018


Abstract: Inflammation is the physiological response to an injury, it could be chemical, thermal, physical and infectious for reparative activity to injury. Recent data suggest that chronic inflammation leads to cancer development. Inflammatory mediators released to surrounding environment due to inflammation by inflammatory cells acts as a defensive or offensive depends on secretion of chemical mediators of inflammation such as growth factors, cytokines activating various transcriptional pathways bring about cell proliferation, angiogenesis further leads to tumor growth. This article describe the role of inflammatory cells and its mediators to development of cancer, various underlying unanswered future challenge questions in association with inflammation and cancer.

Keywords: TLR, PAMPs, DAMPs, TNF-α, IL-1β, IL-6, NF-KB, STAT-3, HIF-1α, TGF-β, Tumor associated macrophages, Tumor associated neutrophils.

Download Full Article

product-logo-jao 1340476205

Incidence of Lung Adenocarcinoma following Recurrent Deep Vein Thrombosis: A Case PresentationPages 29-31

Ali Sharifpour, Siavash Abedi,Masoud Aliyali, Sepideh Safa Navai, Ali Davoodi and Seyyed Abbas Hashemi

https://doi.org/10.6000/1927-7229.2018.07.02.3

Published: 17 April 2018


Abstract: Deep vein thrombosis (DVT) is a common disease that can lead to death. Many studies have looked at the chance of occurrence and the factors affecting thrombosis as one of the complications of cancer. This chance increases in patients with more severe cancer. The progression of cancer and the risk of death in patients with DVT is more severe and with a worse prognosis. But according to our knowledge, there is no accurate report of the incidence and diagnosis of cancer long after thrombosis .In our case, lung adenocarcinoma arose months after the onset of frequent thrombosis in a healthy person. So recommended to consider the risk of developing cancer in patients with recurrent thrombosis.

Keywords: Lung, Adenocarcinoma, Thrombosis.

Download Full Article

product-logo-jao 1340476205

Knowledge and Behavior of Women on Cervical Cancer in the Northern Region of Cameroon
Pages 125-130

Armel Herve Nwabo Kamdje, Georges Kalgong, Paul Takam Kamga, Richard Simo Tagne, Jeremie Mbo Amvene and Charlette Nangue
DOI:
http://dx.doi.org/10.6000/1927-7229.2017.06.03.1

Published: 31 August 2017


Abstract: Background: Cervical cancer is a major cause of women death worldwide. The reduction of the mortality and morbidity of this pathology depends on the early detection based on powerful suitable screening methods, that will lead to optimal treatment strategies. However in some rural region of developing countries, it is very difficult to get access to standard screening methods, alternative screening methods, cheaper and easy to handle are then useful.

Objective: The aim of this work was to test the sensitivity and specificity of VIA (Visual inspection with acetic acid) and VILI (Visual inspection with lugol iodine) as a diagnostic test of cervical cancer compared to the Pap Smear, evaluating the feasibility in health formation in the North Cameroon region, of implementing epidemiological surveillance of cervical cancer based on early diagnosis using the VIA-VILI association

Method: 309 women age 20 to 62 years were recruited in this study, 307 were included in the statistical analyzes. Each woman was screened for cervical cancer by a conventional Smear and visual inspection with acetic acid 5% and the lugol solution.

Results: We found in our study a prevalence of precancerous lesions of cervix at 12.70%. The risks factors of cervical cancer identified are age, matrimonial status, age of first sexual intercourse and parity. The association of VIA and VILI showed a sensitivity, specificity, positive and negative predictive value respectively about 93.58%; 97.01%; 82.01%, 99.04%.

Conclusion: Compared to PAP Smear, VIA or VILI could be used as an alternative screening methods for cervical cancer in developing countries, where it is difficult to access to more accurate test such as colposcopy and biopsy.

Keywords: Sensitivity, specificity, diagnosis, VIA-VILI, cervical cancer.
Download Full Article

OUR STRENGTHS

♦  Worldwide readership
♦  High quality content
♦  Maximum visibility
♦  Efficient publishing
♦  Optional Open Access

Publish your Research

Survey

As an author what type of publishing model you prefer?

780
Open Access
493
Optional Open Access
338
Subscription based
5 Votes left