Effectiveness of Interventions in Enhancing the Mental Health of Persons with Intellectual Disability: A Systematic Literature Review
DOI:
https://doi.org/10.6000/2292-2598.2026.14.01.5Keywords:
Interventions, mental health, intellectual disability, systematic reviewAbstract
Introduction: Mental health conditions are significantly more prevalent among individuals with intellectual disability (ID) compared to the general population, yet tailored interventions remain limited. This review synthesises recent evidence on the effectiveness of interventions designed to enhance mental health outcomes in this group, focusing on approaches adapted to their cognitive and social needs.
Methods: A systematic literature review was conducted following PRISMA guidelines. PubMed, PsycINFO, Web of Science, Scopus, and the Cochrane Library were searched for studies published between 2020 and 2025. A total of 901 records were screened, with 12 empirical studies meeting the inclusion criteria. Eligible studies evaluated interventions targeting mental health outcomes among individuals with ID using quantitative research designs.
Findings: Interventions identified included cognitive-behavioural therapy, mindfulness-based practices, physical and cognitive training, integrative healthcare, peer mentoring, psychoeducation, and technology-assisted approaches. Adapted cognitive-behavioural and mindfulness interventions improved emotional regulation, coping, and quality of life. Physical activity programmes and peer mentoring fostered resilience and social inclusion, while technology-assisted therapies showed feasibility and acceptability. However, outcomes varied according to participant characteristics, delivery methods, and contextual factors. Notably, gaps remain in standardising outcome measures and assessing long-term sustainability.
Conclusion: Evidence suggests that multidisciplinary, individualised, and community-based interventions hold promise for enhancing mental health outcomes in people with ID. Collaborative approaches involving healthcare providers, families, and individuals are essential. Future research should prioritise scalable interventions, professional training, and policy integration to ensure equitable, evidence-based support for this underserved population.
References
Munir KM. Intellectual developmental disorder (intellectual disability). In: The SAGE Handbook of Clinical Neuropsychology. London: Sage; 2023; pp.149-63. DOI: https://doi.org/10.4135/9781529789522.n10
Hassiotis A, Kouroupa A, Jones R, Morant N, Courtenay K, HallI, et al.Clinical and cost evaluation of intensive support team (IST) models for adults with intellectual disabilities who display challenging behaviour: a comparative cohort study protocol. BMJ Open 2021; 11(3): e043358. DOI: https://doi.org/10.1136/bmjopen-2020-043358
Gómez LE, Navas P, Verdugo MÁ, Tassé MJ. Empirically supported psychological treatments: the challenges of comorbid psychiatric and behavioural disorders in people with intellectual disability. World J Psychiatry 2021; 11(11): 1039-52. DOI: https://doi.org/10.5498/wjp.v11.i11.1039
Muralidhar M, Spector A, Hui EK, Liu L, Ali A. A systematic review of psychosocial interventions for people with intellectual disabilities and dementia. Aging Ment Health 2024; 28(3): 385-95. DOI: https://doi.org/10.1080/13607863.2023.2265322
Kim M, Lee S, Jeong IJ, Jeon M, Jung D. Digital interventions for mental health: challenges and opportunities. J Korean Med Assoc 2024; 67(12): 752-61. DOI: https://doi.org/10.5124/jkma.2024.67.12.752
Keller TE, Perry M, Spencer R. Reducing social isolation through formal youth mentoring: opportunities and potential pitfalls. Clin Soc Work J 2020; 48(1): 35-45. DOI: https://doi.org/10.1007/s10615-019-00727-x
Killaspy H, Harvey C, Brasier C, Brophy L, Ennals P, Fletcher J, et al. Community-based social interventions for people with severe mental illness: a systematic review and narrative synthesis of recent evidence. World Psychiatry 2022; 21(1): 96-123. DOI: https://doi.org/10.1002/wps.20940
Vereenooghe L, Westermann K. Feasibility and acceptability of an interactive mental well-being intervention for people with intellectual disabilities: pilot mixed methods study. JMIR Form Res 2019; 3(4): e15190. DOI: https://doi.org/10.2196/15190
Baksh RA, Sheehan R, Hassiotis A, Smith J, Strydom A. Identifying individuals with intellectual disability who access mental health support and are at high risk for adverse clinical outcomes: cohort study. BJPsych Open 2023; 9(6): e183. DOI: https://doi.org/10.1192/bjo.2023.574
Karlsen K, Munkhaugen EK, Fossum HK, Bakken TL, Kildahl AN. Mental health services for adults with intellectual disabilities: a qualitative study of patient characteristics, associated factors and consequent needs for adaptation in assessment and treatment. J Appl Res Intellect Disabil 2025; 38(1): e13315. DOI: https://doi.org/10.1111/jar.13315
Frazier JA, Hanratty L, Weinstock AK. Mental health care needs and access to care for adults with intellectual disabilities. Med Care 2025; 63(1S): 1-7. DOI: https://doi.org/10.1097/MLR.0000000000002089
Hunter E, Sunley J, Richardson S, Hemm C, Dagnan D. A systematic review of training for mainstream mental health professionals working with people with intellectual disabilities and mental health needs. Adv Ment Health Intellect Disabil 2025; 19(1): 36-48. DOI: https://doi.org/10.1108/AMHID-06-2024-0020
Evans E, Howlett S, Kremser T, Simpson J, Kayess R, Trollor J. Service development for intellectual disability mental health: a human rights approach. J Intellect Disabil Res 2012; 56(11): 1098-109. DOI: https://doi.org/10.1111/j.1365-2788.2012.01636.x
Mazza MG, Rossetti A, Crespi G, Clerici M. Prevalence of co-occurring psychiatric disorders in adults and adolescents with intellectual disability: a systematic review and meta-analysis. J Appl Res Intellect Disabil 2020; 33(2): 126-38. DOI: https://doi.org/10.1111/jar.12654
Pouls KPM, Cuypers M, Mastebroek M, Wieland J, Koks-Leensen MCJ, Leusink GL, et al. Mental healthcare for adults with mild intellectual disabilities: population-based database study in Dutch mental health services. BJPsych Open 2023; 9(2): e48. DOI: https://doi.org/10.1192/bjo.2023.31
Taua C, Hepworth J, Neville C. Nurses’ role in caring for people with a comorbidity of mental illness and intellectual disability: a literature review. Int J Ment Health Nurs 2012; 21(2): 163-74. DOI: https://doi.org/10.1111/j.1447-0349.2011.00779.x
Weise J, Trollor JN. Preparedness and training needs of an Australian public mental health workforce in intellectual disability mental health. J Intellect Dev Disabil 2018; 43(4): 431-40. DOI: https://doi.org/10.3109/13668250.2017.1310825
Newman B, Fisher KR, Trollor J. Right to information for people with intellectual disability in Australian mental health policy. J Policy Pract Intellect Disabil 2022; 19(2): 230-8. DOI: https://doi.org/10.1111/jppi.12396
Lewin G, Kousovista R, Abakasanga E, Shivamurthy R, Cosma G, Jun G, et al. Nature and prevalence of long-term conditions in people with intellectual disability: retrospective longitudinal population-based study. BMJ Open 2025; 15(1): 1-10. DOI: https://doi.org/10.1136/bmjopen-2024-090857
Sambamoorthi U, Fulda K, Schneider D, Thakur B, Strenth, YoungR. et al.Intellectual disability (ID) and chronic conditions burden among adults: insights from harmonised electronic health records. Ann Fam Med 2024; 22(1): 6639. DOI: https://doi.org/10.1370/afm.22.s1.6639
Cooper SA, McLean G, Guthrie B, McConnachie A, Mercer S, Sullivan F, et al. Multiple physical and mental health comorbidity in adults with intellectual disabilities: population-based cross-sectional analysis. BMC Fam Pract 2015; 16(1): 110. DOI: https://doi.org/10.1186/s12875-015-0329-3
Donner B, Mutter R, Scior K. Mainstream in-patient mental health care for people with intellectual disabilities: service user, carer and provider experiences. J Appl Res Intellect Disabil 2010; 23(3): 214-25. DOI: https://doi.org/10.1111/j.1468-3148.2009.00527.x
Hughes-McCormack LA, Rydzewska E, Henderson A, MacIntyre C, Rintoul J, et al. Prevalence of mental health conditions and relationship with general health in a whole-country population of people with intellectual disabilities compared with the general population. BJPsych Open 2017; 3(5): 243-8. DOI: https://doi.org/10.1192/bjpo.bp.117.005462
Dew A, Dowse L, Athanassiou U, Trollor J. Current representation of people with intellectual disability in Australian mental health policy: the need for inclusive policy development. J Policy Pract Intellect Disabil 2018; 15(2): 136-44. DOI: https://doi.org/10.1111/jppi.12239
Whittle EL, Fisher KR, Reppermund S, Lenroot R, Trollor J. Barriers and enablers to accessing mental health services for people with intellectual disability: a scoping review. J Ment Health Res Intellect Disabil 2018; 11(1): 69-102. DOI: https://doi.org/10.1080/19315864.2017.1408724
Page MJ, McKenzie JE, Bossuyt PM, Boutron I,Hoffmann TC, Mulrow CD et al.The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 2021; 372: n71. DOI: https://doi.org/10.1136/bmj.n71
Arksey H, O’Malley L. Scoping studies: towards a methodological framework. Int J Soc Res Methodol 2005; 8(1): 19-32. DOI: https://doi.org/10.1080/1364557032000119616
Popay J, Roberts H, Sowden A, Petticrew M.Guidance on the conduct of narrative synthesis in systematic reviews. ESRC Methods Programme 2006.
Power N, Rawlings GH, Bennett C. Evaluating a mindfulness-based group intervention for adults with intellectual disabilities. Adv Ment Health Intellect Disabil 2022; 16(3): 135-46. DOI: https://doi.org/10.1108/AMHID-01-2022-0001
Mills R, Nathan R, Soper P, Michelet F, Stewart AG, Jaydeokar S. Intellectual disability and autism in adults influence psychological treatments for mental health comorbidities. Adv Ment Health Intellect Disabil 2023; 17(2): 61-72. DOI: https://doi.org/10.1108/AMHID-12-2021-0050
Merzbach V, Jewiss M, Scruton A, Gordon D. The effects of prescribed physical and cognitive exercise on life satisfaction, self-efficacy and mood states in adults with Down Syndrome: the MinDSets Study. Int J Environ Res Public Health 2024; 21: 610. DOI: https://doi.org/10.3390/ijerph21050610
De Kuijper G, Jonker J, Kouwer K, Hoekstra PJ, De Bildt A. Integrative care for challenging behaviours in people with intellectual disabilities to reduce challenging behaviours and inappropriate psychotropic drug prescribing compared with care as usual: a cluster-randomised trial. Int J Environ Res Public Health 2024; 21: 950. DOI: https://doi.org/10.3390/ijerph21070950
Verberg F, Helmond P, Otten R, Overbeek G. The online mindset intervention ‘The Growth Factory’ for adolescents with intellectual disabilities: moderators and mediators. J Intellect Disabil Res 2022; 66(1): 817-32. DOI: https://doi.org/10.1111/jir.12970
Barrett BF, Wehmeyer M, Kolb J, Ostermann T, Sappok T. Impact of the emotional development approach on psychotropic medication in adults with intellectual and developmental disabilities: a retrospective clinical analysis. J Intellect Disabil Res 2024; 68(8): 941-53. DOI: https://doi.org/10.1111/jir.13136
Zhong Y, Zhou J, Li N, Xu W, Qi J. Associations between physical activity and emotional and behavioural problems in Chinese children and adolescents with intellectual disabilities. PeerJ 2025; 13(1): 1-17. DOI: https://doi.org/10.7717/peerj.18949
Ugwuanyi LT, Egbe CI, Nnamani AP, Ubah JC,Adaka TA, Adama GN et al. Rational emotive health therapy for the management of depressive symptoms among parents of children with intellectual and reading disabilities in English language. Medicine (Baltimore) 2022; 101(32): e30039. DOI: https://doi.org/10.1097/MD.0000000000030039
Schwartz AE, Young Adult Mental Health/Peer Mentoring Research Team, Kramer JM, Rogers ES, McDonald KE, Cohn ES. Stakeholder-driven approach to developing a peer-mentoring intervention for young adults with intellectual/developmental disabilities and co-occurring mental health conditions. J Appl Res Intellect Disabil 2020; 33(1): 992-1004. DOI: https://doi.org/10.1111/jar.12721
Mullhall P, Taggart L, McDermott G, Slater P, Fitzpatrick B, Murphy MH, et al. ‘Walk Buds’: a walking intervention to increase physical activity, physical fitness, and emotional well-being, in 9-13-year-old children with intellectual disabilities. Results of a clustered randomised feasibility trial. J Appl Res Intellect Disabil 2024; 37(5): e13260. DOI: https://doi.org/10.1111/jar.13260
Hewitt O, Langdon PE, Larkin M. Using experience-based co-design to develop a novel psychological intervention with people with intellectual disabilities and stakeholders. J Appl Res Intellect Disabil 2025; 38: e70022. DOI: https://doi.org/10.1111/jar.70022
Schwartz A, Davern N, Herer A, Peace-Urquilla M, Corey J, Muthuramalingam D, et al. Exploring the acceptability of a peer-delivered mental health intervention to support young adults with intellectual and/or developmental disabilities. J Appl Res Intellect Disabil 2025; 38: e70014. DOI: https://doi.org/10.1111/jar.70014