Polysulfones with Phenylalanine Derivatives as Chiral Selectors – Membranes for Chiral Separation

Authors

  • Jun Isezaki Department of Biomolecular Engineering, Kyoto Institute of Technology, Matsugasaki, Kyoto 606-8585, Japan
  • Masakazu Yoshikawa Department of Biomolecular Engineering, Kyoto Institute of Technology, Matsugasaki, Kyoto 606-8585, Japan
  • Nanwen Li Department of Energy Engineering, Hanyang University, Seoul 133-791, Republic of Korea
  • Gilles P. Robertson Institute for Chemical Process and Environmental Technology, National Research Council of Canada, Ottawa, Ontario K1A 0R6, Canada
  • Michael D. Guiver Institute for Chemical Process and Environmental Technology, National Research Council of Canada, Ottawa, Ontario K1A 0R6, Canada

DOI:

https://doi.org/10.6000/1929-6037.2012.01.01.1

Keywords:

chiral separation, membrane, optical resolution, permselectivity, polysulfone

Abstract

Polysulfone with a derivative of phenylalanyl residue as a chiral selector (PSf-Ac-D-Phe or PSf-Ac-L-Phe) were prepared by polymer reaction of benzylamine-modified polysulfones with N-a-acetyl-D-phenylalanine or N-a-acetyl-L-phenylalanine. Both polysulfones having a chiral selector gave durable self-standing membranes. The specific rotations of those polymers revealed that the chiral selectors were successfully introduced into the polysulfone. PSf-Ac-D-Phe membrane incorporated L-Glu in preference to D-Glu and vice versa. The chiral separation ability was studied by applying a concentration gradient as a driving force for membrane transport. Permselectivities for those two types of membrane reflected their adsorption selectivities. PSf-Ac-D-Phe membrane selectively transported L-Glu and vice versa. Predicted permselectivities by adopting membrane resistance coincided with the observed ones.

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Published

2012-10-05

How to Cite

Isezaki, J., Yoshikawa, M., Li, N., Robertson, G. P., & Guiver, M. D. (2012). Polysulfones with Phenylalanine Derivatives as Chiral Selectors – Membranes for Chiral Separation. Journal of Membrane and Separation Technology, 1(1), 1–8. https://doi.org/10.6000/1929-6037.2012.01.01.1

Issue

Vol. 1 No. 1 (2012)

Section

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