A Smooth Test of Goodness-of-Fit for the Baseline Hazard Function for Time-to-First Occurrence in Recurrent Events: An Application to HIV Retention Data

Authors

  • Collins Odhiambo Strathmore Institute of Mathematical Sciences, Strathmore University, Ole Sangale Road, Nairobi, Kenya
  • John Odhiambo Strathmore Institute of Mathematical Sciences, Strathmore University, Ole Sangale Road, Nairobi, Kenya
  • Bernard Omolo Division of Mathematics and Computer Science, University of South Carolina-Upstate, 800 University Way, Spartanburg, South Carolina, USA

DOI:

https://doi.org/10.6000/1929-6029.2017.06.03.2

Keywords:

BBS model, Hazard function, Loss to follow-up, Neyman’s smooth test, Recurrent events, Retention in HIV care

Abstract

Motivated by HIV retention, we present an application of the smooth test of goodness-of-fit under right-censoring to time to first occurrence of a recurrent event. The smooth test applied here is an extension of Neyman’s smooth test to a class of hazard functions for the initial distribution of a recurrent failure-time event. We estimate the baseline hazard function of time-to-first loss to follow-up, using a Block, Borges and Savits (BBS) minimal repair model of the data (n = 2,987,72% censored). Simulations were conducted at various percentages of censoring to assess the performance of the smooth test. Results show that the smooth test performed well under right-censoring.

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Published

2017-08-03

How to Cite

Odhiambo, C., Odhiambo, J., & Omolo, B. (2017). A Smooth Test of Goodness-of-Fit for the Baseline Hazard Function for Time-to-First Occurrence in Recurrent Events: An Application to HIV Retention Data. International Journal of Statistics in Medical Research, 6(3), 104–113. https://doi.org/10.6000/1929-6029.2017.06.03.2

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