jbas
3-Aminopropyltriethoxysilane-Based Bioanalytical Procedures for Potential In Vitro Diagnostics DOI: http://dx.doi.org/10.6000/1927-5129.2014.10.62 Published: 11 November 2014 |
Editorial |
A Case of Sigmoid Colon Cancer in which Somatic Pain was Rapidly Alleviated after Panitumumab Administration Despite Tumor Progression |
Abstract: We present a 72-year-old woman with sigmoid colon cancer in whom the somatic pain was alleviated rapidly after the administration of anti-epidermal growth factor antibodies. Our patient had received 4 cycles of FOLFIRI therapy (irinotecan, 5-fluorouracil, and leucovorin) in combination with panitumumab (Pmab) for the treatment of unresectable primary cancer accompanied with multiple liver metastases and peritonitis carcinomatosa. As grade 3 paronychia eventually occurred, chemotherapy was stopped. After recovery of the grade 3 paronychia, Pmab was re-introduced and administered every alternate cycle to reduce the extent of adverse events. The patient had complained of somatic pain in the lower right abdomen just before re-initiating Pmab administration. The pain intensity decreased immediately after the administration of Pmab. On the next day her pain had remarkably alleviated and she was free from pain for a week. This phenomenon was repeatedly observed. After the re-introduction of Pmab, tumor response was evaluated on computed tomography, which showed progressive disease. We demonstrated that Pmab was effective in the alleviation of somatic pain, although the size of the tumors gradually increased. Download Full Article |
A Comparative Study of Production Performance and Egg Quality Parameters of Naked-Neck and Indigenous Aseel Chicken of Pakistan DOI: http://dx.doi.org/10.6000/1927-5129.2014.10.21 Published: 21 April 2014 |
Abstract: The present study was conducted to evaluate production performance and egg quality of four different varieties of native Aseel chicken in comparison with naked neck. A total of 105 adult chickens, 21 birds from each of four varieties of Aseel namely Lakha, Mushki, Peshawari and Mianwali, and 21 birds from naked neck, were maintained separately. The data of daily egg production, daily egg weight and weekly egg quality were calculated for up to ten weeks and analyzed under Completely Randomized Design (CRD) through SAS 9.1 software. Comparison among treatment means were made through Duncan’s Multiple Range (DMR) test. The results showed that egg production of Naked-neck (47.42) was significantly higher (P<0.05) than that of Mushki (34.08), Lakha (31.43), Mianwali (29.59) and Pesahwari (28.7). However,egg weight of Naked-neck (57.52) and Peshwari (55.65) was significantly greater (P<0.05) compared with lakha (54.03), Mushki (53.7) and Mianwali (51.62). Regarding egg quality traits, shell % of Peshawari (13.57) and Nakedneck (13.16) was significantly higher (P<0.05) than that of Lakha (11.89), Mushki (10.19) and Mianwali (9.36). Similarly, Haugh Unit Score of Naked-neck (82.76) and Peshawari (81.95) was significantly greater (P<0.05) than other varieties of Aseel. Albumen % was significantly higher in Mushki (61.83) variety (P<0.05) while yolk % was significantly higher in Mianwali (59.36) variety of Aseel (P<0.05) whereas yolk index showed non-significant (P>0.05) difference in Naked-neck and all varieties of Aseel. Keywords: Production performance, Egg quality, Genetic potential, Naked-neck, Aseel.Download Full Article |