Does Side Matter?: A Retrospective Study Exploring the Side Preference of Abnormal Hypermetabolic Adrenal Activity
Pages 70-73

Michael Staton, Alex Yi, Ohwook Kwon and Xueren Zhao

DOI: http://dx.doi.org/10.6000/1929-2279.2017.06.03.3

Published: 8 Dec 2017

Abstract: Hypermetabolic adrenal activity can be seen on F-18 FDG positron emission tomography (F-18 FDG PET) in patients undergoing evaluation for malignancy. The adrenal glands are bilateral organs that are anatomically similar to each other with no differences to arterial supply. They are also a common site of metastases. A retrospective study of 1135 patients with tumors at a veteran hospital was performed to see if hypermetabolic adrenal activity was more common on the left or right. Chi-square analysis demonstrated a significant side preference, with hypermetabolic activity occurring significantly more often in the left adrenal gland.

Keywords: Adrenal, PET/CT, incidentaloma, F18-FDG.

Short Commentary: The Role of Thoracic Radiotherapy in Extensive Stage Small Cell Lung Carcinoma – A Concise Review of the Latest Literature - Pages 74-77

Irfan Ahmad and Kundan Singh Chufal

DOI: http://dx.doi.org/10.6000/1929-2279.2017.06.04.1

Published: 1 January 2018

Abstract:

Keywords:

Twice Operations for Parotid Metastasis of Nasopharyngeal Carcinoma Patient after Radical Intensity-Modulated Radiotherapy: A Case Report - Pages 78-80

Guangmou Tan, Weiquan Chen, Xiaojun Tan, Haiyan Huang, Ke Liu and Hong Yang

DOI: http://dx.doi.org/10.6000/1929-2279.2017.06.04.2

Published: 1 January 2018

Abstract: The surgery treatment of parotid metastasis of nasopharyngeal carcinoma(NPC) after parotid-gland-sparing IMRT is rare report. We present such a case of NPC patient cT2N2M0 with parotid lymph node metastasis after parotid-gland-sparing IMRT patient who accepted the second operation after the first failure parotid section. This case reminded us that neck dissection added the whole parotid glandresection may be an appropriate method to treat this type of patients.

Keywords: Nasopharyngeal carcinoma, Parotid lymph node metastasis, Prognosis, Intensity-modulated radiotherapy, Surgery.

A Guide for Cancer Pain Management in Latin America - Pages 81-96

Joseph V. Pergolizzi, Jr., Robert B. Raffa, Emilio Esteban Gonzalez and Jo Ann LeQuang

DOI: http://dx.doi.org/10.6000/1929-2279.2017.06.04.3

Published: 1 January  2018

Abstract: The surgery treatment of parotid metastasis of nasopharyngeal carcinoma(NPC) after parotid-gland-sparing IMRT is rare report. We present such a case of NPC patient cT2N2M0 with parotid lymph node metastasis after parotid-gland-sparing IMRT patient who accepted the second operation after the first failure parotid section. This case reminded us that neck dissection added the whole parotid glandresection may be an appropriate method to treat this type of patients.

Keywords: Nasopharyngeal carcinoma, Parotid lymph node metastasis, Prognosis, Intensity-modulated radiotherapy, Surgery.

Perioperative Effects of Surgery, Anesthesia and Analgesics Associated with Cancer Progression: A Review  - Pages 1-20

Keishla M. García, Karla M. Flores, Adriana Falcón, Charlynne De Jesus, Loida Del Rio, Laura C. Rivera, Michelle Marquez, Santos Ortiz, Gretchen Sandoval, Alejandro Ruiz, Fabiola Rodriguez, Frances Gonzalez, Kenneth Cintron, Miguel J. Berdiel, Jorge Duconge, Maricelly Santiago, Ines Alfaro and Michael J. Gonzalez

DOI: http://dx.doi.org/10.6000/1929-2279.2018.07.01.1
Published: 28 February  2018

Abstract: One of the most common treatments available for cancer patients is surgical removal of the malignant tumor; its long-term implications, however, are still little-known. The purpose of this review is to look at the perioperative effects and determine if there is any correlation between surgery, anesthetics and analgesics, and cancer progression, in the form of cancerous tumor growth and progression and patient survival, within the Puerto Rican population. A retrospective literature review was conducted. Current data suggest that surgery is associated with an increase in cancer proliferation and metastasis, for various reasons such as angiogenesis enhancement and bloodstream migration. Also, it was found that some anesthetics and analgesics have been associated with cancer progression, based on the peri- and postoperative immune status of the patient. Thiopental, ketamine, isoflurane, halothane and some opioids were positively correlated with cancer progression given their role in immunosuppression; while propofol, lidocaine, ropivacaine and bupivacaine were negatively correlated with tumor progression given their immune enhancement. Others, like sevoflurane, nitrous oxide, and etomidate showed inconclusive correspondence. Therefore, it was concluded that immune system boosting anesthetics and analgesics can reduce cancer progression in a patient that has undergone surgical resection. For further research and since the available data are not extensive, other variables such as age, sex, stressors and comorbidities could be considered to better understand the mechanism in which the chemicals hereby studied can cause cancer progression.

Keywords: Anesthetics, analgesics, opioids, cancer, metastasis, recurrence, immunosuppression.